Ankylosing Spondylitis Disease Activity Score with ESR (ASDAS-ESR)

Tx: Primary tumor cannot be assessed

T0: No evidence of primary tumor

Tis: Carcinoma in situ

T1: Tumor restricted to any 1 subsite, with or without bony invasion

T2: Tumor invading 2 subsites in a single region or extending to involve an adjacent region within the nasoethmoidal complex, with or without bony invasion

T3: Tumor extends to invade the medial wall or floor of the orbit, maxillary sinus, palate, or cribriform plate

T4a: Tumor invades any of the following: anterior orbital contents, skin of the nose or cheek, minimal extension to the anterior cranial fossa, pterygoid plates, sphenoid or frontal sinuses

T4b: Tumor invades any of the following: orbital apex, dura, brain, middle cranial fossa, cranial nerves other than maxillary division of trigeminal nerve (V2), nasopharynx, or clivus

Nx: Regional lymph nodes cannot be assessed

N0: No regional lymph node metastasis

N1: Metastasis in a single ipsilateral lymph node ≤ 3 cm in greatest dimension and no extranodal extension

N2: Metastasis in a single ipsilateral lymph node > 3 cm but not > 6 cm in greatest dimension and no extranodal extension; or metastases in multiple ipsilateral lymph nodes, none > 6 cm in greatest dimension and no extranodal extension; or in bilateral or contralateral lymph nodes, none > 6 cm in greatest dimension and no extranodal extension

N3: Metastasis in a lymph node > 6 cm in greatest dimension and no extranodal extension; or in a single ipsilateral node > 3 cm in greatest dimension and extranodal extension; or multiple ipsilateral, contralateral, or bilateral nodes, any with extranodal extension; or a single contralateral node of any size and extranodal extension

M0: No distant metastasis

M1: Distant metastasis present