The Assessment of Diastolic Dysfunction Severity (with LV structural pathology) is a clinical tool designed to evaluate the severity of diastolic dysfunction in patients with structural pathology of the left ventricle. This tool is particularly useful in stratifying patients based on the severity of their diastolic dysfunction, which can guide therapeutic decisions and provide prognostic information.
The primary components of this assessment tool are three measurable parameters: the average E/e' ratio, peak TR velocity, and left atrial volume index. Each of these parameters is assigned a score of 1 if it exceeds a certain threshold. Specifically, an average E/e' ratio greater than 14, a peak TR velocity greater than 2.8 m/s, and a left atrial volume index greater than 34 mL/m^2 each contribute one point to the total score.
The total score is then used to determine the severity of diastolic dysfunction. A score of 2 or more indicates grade 2 diastolic dysfunction, while a lower score indicates grade 1 diastolic dysfunction. This stratification allows clinicians to better understand the patient's condition and tailor treatment accordingly.
Reference
Sherif F Nagueh, Otto A Smiseth, Christopher P Appleton et al. Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2016 Apr;29(4):277-314.
Open reference URL