Calcium Correction for Hypoalbuminemia and Hyperalbuminemia
Calculator
When to use
Serum calcium (mg/dL)
mg/dL
mmol/L
Albumin (g/dL)
g/dL
g/L
Normal albumin (g/dL)
g/dL
g/L
Calculation
Please enter all the required inputs.
The Calcium Correction for Hypoalbuminemia and Hyperalbuminemia, or simply Calcium Correction for Albumin, is a clinical tool to adjust serum calcium levels based on the patient's albumin concentration. It is particularly applicable to patients with hypoalbuminemia (low albumin levels) or hyperalbuminemia (high albumin levels), conditions often seen in critically ill patients, those with liver disease, nephrotic syndrome, malnutrition, and burns.
The clinical utility of this calculator lies in its ability to provide a more accurate assessment of the patient's calcium status. Serum calcium levels can be influenced by albumin concentrations, as albumin is the primary protein that binds calcium in the blood. Therefore, in conditions where albumin levels are abnormal, the total serum calcium may not accurately reflect the patient's true calcium status. The Calcium Correction for Hypoalbuminemia and Hyperalbuminemia calculator corrects the total serum calcium level based on the albumin level, providing a more accurate reflection of the patient's ionized calcium level, which is the physiologically active form of calcium.
There are no specific exclusion criteria for the use of this calculator. However, it should be noted that this correction is an estimation and may not be accurate in all clinical situations. For instance
Reference
R B Payne, A J Little, R B Williams et al. Interpretation of serum calcium in patients with abnormal serum proteins. Br Med J. 1973 Dec 15;4(5893):643-6.
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