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Abnormal uterine bleeding
What's new
Updated 2024 SOGC guidelines for the management of abnormal uterine bleeding .
Background
Overview
Definition
AUB is defined as bleeding from the uterine corpus that is abnormal in regularity, volume, frequency, or duration and occurs in the absence of pregnancy.
1
Pathophysiology
The key pathophysiological mechanisms of AUB include hormonal imbalances, endometrial abnormalities, and coagulation disorders. Hormonal imbalances, such as anovulation, can lead to AUB, as it is one of the most common causes of this condition.
2
Epidemiology
The prevalence of AUB in the US is estimated at around 16.4% in 2019-2021.
3
Disease course
The clinical presentations of AUB can vary. It can present as heavy menstrual bleeding, irregular menstrual bleeding, intermenstrual bleeding, or even postmenopausal bleeding.
2
Prognosis and risk of recurrence
The prognosis is generally benign, but it can significantly impact a woman's QoL due to its direct influence on healthcare resources, costs, and utilization.
4
Guidelines
Key sources
The following summarized guidelines for the evaluation and management of abnormal uterine bleeding are prepared by our editorial team based on guidelines from the American Academy of Family Physicians (AAFP 2024,2019), the Society of Obstetricians and Gynaecologists of Canada (SOGC 2024,2019,2018), the American College of Radiology (ACR 2020), the American College of Obstetricians and Gynecologists (ACOG 2019,2013,2012), and the Society ...
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