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Acute pericarditis
Background
Overview
Definition
Acute pericarditis is a disease characterized by acute inflammation of the pericardium.
1
Pathophysiology
Most cases of acute pericarditis are idiopathic (80-90%) and assumed to be due to viral infection. Other important causes include post-cardiac injury syndromes, connective tissue diseases (such as SLE), and cancer.
2
Epidemiology
In the US, the incidence of acute pericarditis requiring hospitalization is estimated at 26 cases per 100,000 person-years.
3
Disease course
Inflammation of the pericardium results in the formation of a pericardial effusion, which may progress to cardiac tamponade and obstructive shock.
2
Prognosis and risk of recurrence
Acute pericarditis is associated with 5.7% all-cause mortality at 30 days, and 17.3% all-cause mortality at 1 year.
3
Guidelines
Key sources
The following summarized guidelines for the evaluation and management of acute pericarditis are prepared by our editorial team based on guidelines from the American Academy of Family Physicians (AAFP 2024), the European Society for Microbiology and Infectious Diseases (ESCMID 2022), the European Society of Cardiology (ESC/ESTRO/EHA/IC-OS 2022), the Infectious Diseases Society of America (IDSA/ACR/AAN 2021), the Society of Cardiovascular Computed ...
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