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Yellow fever
Guidelines
Key sources
The following summarized guidelines for the management of yellow fever are prepared by our editorial team based on guidelines from the World Health Organization (WHO 2025).
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Medical management
Fluid management: as per WHO 2025 guidelines, consider implementing protocolized oral fluid treatment in patients with suspected or confirmed non-severe arboviral disease.
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implement monitoring of hydration and prevention of dehydration in all patients. Provide a cup or other means of measuring oral intake and give advice on how to record the amount taken. Administer volumes of fluids based on age and underlying medical conditions, such as congestive HF, CKD. ⁄
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Antipyretic and analgesics
Corticosteroids
IVIG
N-acetylcysteine
Experimental treatment
Therapeutic procedures
Blood transfusion: as per WHO 2025 guidelines, avoid administering prophylactic platelet transfusion in patients with suspected or confirmed severe arboviral disease and a platelet count of < 50, 000/mcL who have no active bleeding.
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consider administering platelet transfusion in specific circumstances, such as prevention of hemorrhage during surgery or other invasive procedures, and in patients receiving pre-existing anticoagulation treatment. ⁄